The Selective Personalized Radio-Immunotherapy for locally advanced NSCLC Trial (SPRINT)

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Non-small Cell Lung Cancer
  • Age: Between 18 years - 100 years
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1) Unresectable stage II or III, previously untreated, pathologically proven NSCLC with measurable disease 2) Whole body PET/CT within 42 days prior to study entry demonstrating hypermetabolic pulmonary lesion(s) and/or thoracic lymph node(s). If PET/CT was obtained more than 42 days prior to study entry and is not repeated, CT within 28 days prior to study entry demonstrating no evidence of metastatic disease is required. 3) MRI of the brain or head CT with contrast within 42 days prior to study entry. 4) PFTs within 42 days of study entry

You may not be eligible for this study if the following are true:

  • 1) Systemic therapy for lung cancer within the past year. 2) Prior therapy with an anti-PD-1, anti-PD-L1, or anti-PD-L2 agent or with an agent directed to another stimulatory or co-inhibitory T-cell receptor. 3) Has known psychiatric or substance abuse disorders that would interfere with cooperation with the requirements of the trial. 4) Pregnancy


If you are registered as a volunteer, please log in to contact the study team/express interest in this study.