Site for ACNS1833: A Phase 3 Randomized Non-Inferiority Study of Carboplatin and Vincristine versus Selumetinib (NSC# 748727 IND# 77782) in Newly Diagnosed or Previously Untreated Low-Grade Glioma (LGG) not associated with BRAFV600E Mutations or Systemic

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Low Grade Astrocytoma (who I Or Ii)
    Low Grade Glioma
  • Age: Between 2 Year(s) - 21 Year(s)
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1) Patients must have a body surface area (BSA) of >= 0.5 m^2 at enrollment. 2) Patients must have non-neurofibromatosis type 1 (non-NF1) low-grade glioma (LGG) without a BRAFV600E mutation as confirmed by Rapid Central Pathology and Molecular Screeni

You may not be eligible for this study if the following are true:

  • 1) Patients must not have received any prior tumor-directed therapy including chemotherapy, radiation therapy, immunotherapy, or bone marrow transplant.


If you are registered as a volunteer, please log in to contact the study team/express interest in this study.

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