A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants with Melanoma (KEYNOTE-U02): Substudy 02A

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Melanoma
  • Age: Between 18 - 100 Years
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1) Has histologically or cytologically confirmed melanoma. 2) Has unresectable Stage III or Stage IV melanoma. 3) Has progressed after receiving prior PD-1 therapy 4) Has the presence of at least 1 measurable lesion by CT or MRI 5) Received no more than 3 prior regimens

You may not be eligible for this study if the following are true:

  • 1) Has a diagnosis of immunodeficiency or is receiving chronic systemic steroid therapy (in dosing exceeding 10 mg daily of prednisone equivalent) or any other form of immunosuppressive therapy within 7 days before the first dose of study intervention. 2) Has a known additional malignancy that is progressing or requires active treatment within the past 2 years.


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