Expanded Access to ONC201 for Patients with H3 K27M-mutant and/or Midline Gliomas

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
  • Age: Between 0 Year(s) - 100 Year(s)
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Patient must weigh at least 10kg. 2. Patient meet one or more of the criteria below: Arm A a. Central nervous system tumor that is positive for the H3 K27M mutation (performed in a laboratory with CLIA or equivalent certification); b. Central n

You may not be eligible for this study if the following are true:

  • 1. Qualifies for participation in an ongoing ONC201 or ONC206 clinical trial. 2. Previously or currently participating in an ONC201 clinical trial or expanded access protocol. 3. Current or planned participation in a study of an investigational agen


If you are registered as a volunteer, please log in to contact the study team/express interest in this study.

Contact the research team to learn more about this study.

By clicking "Contact Research Team", your contact information will be sent securely to the research staff associated with the study. You will also receive a copy of this email in your inbox, as well as other notifications to determine your participation status in the study.