Perlmutter Cancer Center

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

• Conditions:
  Brain Metastases
• Age: Between 18 years - 100 years
• Gender: Male or Female

• Other Inclusion Criteria:
  

  1. Eastern Cooperative Oncology Group (ECOG) performance status of 0-1, or 2 if this is an acute deterioration (i.e. drop to a performance status of 2, within 4 weeks of Screening). 2. Previous history of solid tumor brain metastasis of any origin. 3. Histopathological confirmation of the primary solid tumor or a metastatic site within 4 years of Screening (Visit 1). 4. Previous radiation therapy of brain metastatic lesion(s) completed at least 8 weeks before Screening. Form of radiotherapy may include stereotactic radiosurgery or whole brain radiotherapy.
  

You may not be eligible for this study if the following are true:

• 1. Pregnant or breastfeeding during participation in the study, or, where applicable, unwilling to abstain from sexual conduct for 24 hours post-18F-fluciclovine injection. 2. Subjects with active hematological malignancy.