Site for Randomized Phase II/III Trial of Surgery and Postoperative Radiation Delivered with Concurrent Cisplatin Versus Docetaxel Versus Docetaxel and Cetuximab for High-Risk Squamous Cell Cancer of the Head and Neck

Brief description of study

The purpose of the study is to determine whether docetaxel alone is as active as docetaxel and cetuximab combination and whether either taxane-based regimen is better than cisplatin monotherapy. Participants will receive one of the following treatments: standard treatment (radiation therapy and cisplatin), experimental treatment (radiation therapy and docetaxel), or experimental treatment (radiation therapy, docetaxel, and cetuximab). All of the drugs are commercially available, however the combination of drugs in this study is considered experimental.

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