A Phase IIa Open-label Clinical Trial to Evaluate the Safety Pharmacokinetics Pharmacodynamics and Efficacy of BP1001 (a Liposomal Grb2 Antisense Oligonucleotide) in Combination with Venetoclax plus Decitabine in Patients with Acute Myeloid Leukemia (AML) Who Are Ineligible for Intensive Induction Therapy

Brief description of study

A Phase IIa, Open-label, Clinical Trial to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of BP1001 (a Liposomal Grb2 Antisense Oligonucleotide) in Combination with Venetoclax plus Decitabine in Patients with Acute Myeloid Leukemia (AML) Who Are Ineligible for Intensive Induction Therapy


Clinical Study Identifier: s19-01800
ClinicalTrials.gov Identifier: NCT02781883
Principal Investigator: Mohammad Maher Abdul Hay.
Other Investigators: Kenny Tai, Gabrielle C Barshay, Sofia Aziz, Jun Han Choi, Shella Saint Fleur-Lominy, David Kaminetzky.


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