Perlmutter Cancer Center

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

• Conditions:
  Brain Metastases
• Age: Between 18 years - 100 years
• Gender: Male or Female

• Other Inclusion Criteria:
  

  1) Histologically confirmed parenchymal metastatic disease to the brain from any solid tumor. 2) Measurable CNS disease (=10 mm). 3) Ability to obtain MRIs with contrast. 4) New or progressive CNS lesions after systemic therapy or prior radiotherapy.
  

You may not be eligible for this study if the following are true:

• 1) Patients with personal history of any of the following conditions: syncope of cardiovascular etiology, ventricular arrhythmia of pathological origin (including, but not limited to, ventricular tachycardia and ventricular fibrillation), or sudden cardiac arrest, are excluded. 2) Patients with active bacterial infection (requiring intravenous [IV] antibiotics at time of initiating study treatment), fungal infection, or detectable viral infection (such as known human immunodeficiency virus positivity or with known active hepatitis B or C [for example, hepatitis B surface antigen positive] are excluded.