NSABP B51: Phase 3 Trial Evaluating Post-Mastectomy Chestwall And Post-Lumpectomy Regional Nodal Irradiation In Patients With Positive Axillary Nodes Before Neoadjuvant Chemotherapy who Convert To Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy

Brief description of study

If you have been diagnosed with breast cancer and have been treated with chemotherapy followed by breast surgery called a lumpectomy (surgical removal of tumor from the breast) you may qualify to participate in a clinical study evaluating the use of radiation on both the breast and the lymph nodes as opposed to radiation to the breast only. The main goal of this randomized phase III, study is to determine if radiation to the breast and lymph node is better at keeping breast cancer from returning than radiation to the breast only. The study will also investigate if giving radiation as described above will help women live longer and how the study treatment affects patients’ quality of life both physically and emotionally.


Clinical Study Identifier: s14-01289
ClinicalTrials.gov Identifier: NCT01872975
Principal Investigator: Carmen A. Perez
Currently Recruiting

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