GMCI plus Standard of Care Immune Checkpoint Inhibitor for Stage III/IV NSCLC Patients

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GMCI plus Standard of Care Immune Checkpoint Inhibitor for Stage III/IV NSCLC Patients

Brief description of study

The purpose of the trial is to assess the safety and efficacy of the Gene Mediated Cytotoxic Immunotherapy (GMCI) added to standard of care immune checkpoint inhibitor (ICI) for non-small Cell Lung Cancer (NSCLC) patients. We want to know if GMCI can increase the number of patients who will respond to the continued ICI. Patents may receive whatever standard of care therapy as indicated by their disease such as maintenance chemotherapy, bevacizumab , or focal radiation.

Clinical Study Identifier: s19-01928

ClinicalTrials.gov Identifier: NCT04495153

Principal Investigator: Daniel H. Sterman.

Other Investigators: Elaine Shum, Jennifer Wu, Ian John Henderson, Jessica Wang, Cristian C Papazoglu Statescu, Jeffrey G Schneider, Elsa Bahiru, Avital Benson, Natalia Cherkassky, Lea Azour, Edna Shifteh, Lauren G. Khanna, William H. Moore, Samaan Rafeq, Jamie L. Bessich, Joshua K Sabari, Abraham Chachoua, Vivek Murthy, Sally Lau, Salman Rafi Punekar, Melissa L Martinez, Marissa Rybstein, Daniel Da Costa, Mary Lynn R Nierodzik, David Mendoza, Vamsidhar Velcheti.

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Perlmutter Cancer Center

Clinical Trials & Research Studies