A First in Human Study of theMenin-KMT2A (MLL1)Inhibitor JNJ-75276617 in Participants with Acute Leukemia

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Acute Leukemia
  • Age: Between 18 Year(s) - 100 Year(s)
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1) Relapsed or refractory acute leukemia (ALL or AML) and has exhausted, or is ineligible for, available therapeutic options. 2) Acute leukemia harboring KMT2A (eg, gene rearrangement/translocation, partial tandem duplication,or wild-type amplificatio

You may not be eligible for this study if the following are true:

  • 1) Acute promyelocytic leukemia. 2) Known CNS involvement. 3) Prior solid organ transplantation. 4) Cardiovascular disease that is uncontrolled or that was diagnosed within 6 months prior to the first dose of study treatment.


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