Perlmutter Cancer Center

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

• Conditions:
  Acute Leukemia
• Age: Between 18 Year(s) - 100 Year(s)
• Gender: Male or Female

• Other Inclusion Criteria:
  

  1) Relapsed or refractory acute leukemia (ALL or AML) and has exhausted, or is ineligible for, available therapeutic options. 2) Acute leukemia harboring KMT2A (eg, gene rearrangement/translocation, partial tandem duplication,or wild-type amplification)or NPM1(eg,Exon 12 frameshift) alterations. 3) A woman of childbearing potential must have a negative highly sensitive serum ß-human chorionic gonadotropin at screening and within 48 hours prior to the first dose of study treatment.
  

You may not be eligible for this study if the following are true:

• 1) Acute promyelocytic leukemia. 2) Known CNS involvement. 3) Prior solid organ transplantation. 4) Cardiovascular disease that is uncontrolled or that was diagnosed within 6 months prior to the first dose of study treatment.