AGCT1531: A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs.Cisplatin for Standard Risk Pediatric and Adult Patients with Germ Cell Tumors

Brief description of study

The purpose of the study is to minimize toxicity by reducing therapy while maintaining current survival rates in the treatment of pediatric, adolescent and young adult patients with standard risk non-seminomatous germ cell tumors. We want to know event-free survival of a carboplatin vs. cisplatin-based regimen and would like to determine if complete surgical resection followed by surveillance can improve overall survival rates.


Clinical Study Identifier: s19-01586
ClinicalTrials.gov Identifier: NCT03067181
Principal Investigator: Sharon L Gardner.


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