A Phase 1 and 2a trial of LAVA-1207 in patients with therapy refractory metastatic castration resistant prostate cancer

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Prostate Cancer
  • Age: Between 18 Year(s) - 100 Year(s)
  • Gender: Male
  • Other Inclusion Criteria:
    1) Male patient with mCRPC as defined by PCWG3 criteria (histologically confirmed adenocarcinoma; adenocarcinoma with =10% small-cell or neuroendocrine features is allowed). 2) Brain metastasis are allowed as long as the patient’s symptoms are well controlled. Patients will be unlikely to tolerate or derive clinically meaningful benefit from other available therapy. 3) Patient should have failed at least 1 line of taxane-based chemotherapy or is deemed medically unsuitable to be treated with a taxane regimen.

You may not be eligible for this study if the following are true:

  • 1) Other malignancies within the last 2 years except adequately treated carcinoma in situ, basal or squamous cell skin carcinoma. 2) Uncontrolled or severe intercurrent medical condition. 3) Positive serological testing for human immunodeficiency virus (HIV) antibody. 4) Positive serological hepatitis B surface antigen [HBsAg] and hepatitis B core antibody (anti-HBc) negative, and hepatitis C virus antibody.

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