A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants with Melanoma (KEYMAKER-U02): Substudy 02C

Brief description of study

Substudy 02C is part of a larger research study that is testing experimental treatments for melanoma, a type of skin cancer. The larger study is the umbrella study. The goal of substudy 02C is to evaluate the safety and efficacy of investigational treatment arms in participants with Stage III melanoma who are candidates for neoadjuvant therapy to identify the investigational agent(s) that, when used in combination, are superior to the current treatment options/historical control available.


Clinical Study Identifier: s21-00757
ClinicalTrials.gov Identifier: NCT04303169
Principal Investigator: Janice Mehnert.
Other Investigators: Nila Theresa De La Rosa, Maya Dimitrova, Kathleen M Madden, Jeffrey S. Weber.


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