A Phase 1 First in human Dose Escalation and Expansion Multicenter Study of XMT-1660 in Participants with Solid Tumors
Are you eligible to participate in this study?
You may be eligible for this study if you meet the following criteria:
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Conditions: Previously Treated Participants With Metastatic Tnbc, Hr+/her2- Or Her2+ Breast Cancer, Endometrial Cancer, Or Ovarian, Fallopian Tube, Or Primary Peritoneal Cancer
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Age: Between 18 Year(s) - 100 Year(s)
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Gender: Female
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Other Inclusion Criteria:
- Participant has proven recurrent or advanced solid tumor and has disease progression after treatment with available anti-cancer therapies known to confer benefit or is intolerant to treatment.
- Participant must have cardiac left ventricular ejection fraction =50%
- Participant must have adequate organ function within 14 days prior to cycle 1, day 1 of treatment
- ER+ breast cancer: must have had prior hormonal therapy
- TNBC: must have had prior chemotherapy
You may not be eligible for this study if the following are true:
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- Participant has had major surgery within 28 days of starting study treatment, systemic anticancer therapy within the time period of 28 days.
- Has a diagnosis of additional malignancy that required active treatment.
- Participants with human immunodeficiency virus (HIV) infection are excluded from study entry. An HIV test is required during Screening.
If you are registered as a volunteer, please log in to contact the study team/express interest in this study.