Melanoma Margins Trial (MelMarT): A Phase III Multi-Centre Multi-National Randomised Control Trial Investigating 1cm v 2cm Wide Excision Margins for Primary Cutaneous Melanoma

Brief description of study

This study will determine whether there is a difference in disease free survival for patients treated with either a 1cm excision margin or 2cm margin for clinical stage II (pT2b-pT4b) primary cutaneous melanoma. The study is designed to be able to prove or disprove that there is no difference in risk of melanoma recurrence between the two groups of patients. This study is designed to show that the risk of long-term pain associated with surgery can be reduced.


Clinical Study Identifier: s22-00510
ClinicalTrials.gov Identifier: NCT03860883
Principal Investigator: Erica Brooke Friedman.
Other Investigators: Nila Theresa De La Rosa, Maya Dimitrova, Gary B Deutsch, Zachary Brown, Marianna Shvartsbeyn, Jeffrey S. Weber, George Jour, Richard L Shapiro, Hui C Tsou, Kathleen M Madden, Janice Mehnert.


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