EVEREST-1: A Seamless Phase 1/2 Study to Evaluate the Safety and Efficacy of A2B530 an Autologous Logic-gated Tmod CAR T in Heterozygous HLA-A*02 Adults with Recurrent Unresectable Locally Advanced or Metastatic Solid Tumors That Express CEA and Have

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Advanced Or Metastatic Solid Tumors
  • Age: Between 18 Year(s) - 99 Year(s)
  • Gender: Male or Female
  • Other Inclusion Criteria:
    To participate in the study the following conditions must be met:
    1. Has tissue that shows a specific genetic marker called LOH of HLA-A*02:01 by NGS, and have undergone a successful apheresis and PBMC processing, and there are enough cells stor

You may not be eligible for this study if the following are true:

  • You will not be able to participate in the study if you have:
    1. Illness that can be treated locally (in a specific part of the body) or with a standard medical treatment that can cure the disease and is not just meant to relieve symptoms.


If you are registered as a volunteer, please log in to contact the study team/express interest in this study.

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