A Phase 3 Randomized Placebo-Controlled Double-Blind Multicenter Trial of Selinexor in Maintenance Therapy After Systemic Therapy for Patients with P53 Wild-Type Advanced or Recurrent Endometrial Carcinoma (GOG 3083)

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A Phase 3 Randomized Placebo-Controlled Double-Blind Multicenter Trial of Selinexor in Maintenance Therapy After Systemic Therapy for Patients with P53 Wild-Type Advanced or Recurrent Endometrial Carcinoma (GOG 3083)

Brief description of study

The purpose of this research study is to further evaluate the safety and effectiveness of selinexor for maintenance in patients with TP53 wild-type endometrial cancer.

Clinical Study Identifier: s22-01114

ClinicalTrials.gov Identifier: NCT05611931

Principal Investigator: Bhavana Pothuri.

Other Investigators: Christina Grace Wilson, Kent Chan, Michelle Diane Swanson Lightfoot, Emeline Mariam Aviki, Jaime Lynn Moyles, Edward A Jimenez, Erin Annette Reese, Fabia Brisard Pierrot, Caitlin Elizabeth Ryan, Whitfield B. Growdon, Deanna Gerber, Eva Chalas-Westermann, Alexander A Hindenburg, Jagdeep Raince, Marina Stasenko, Kelly A Levine, Olivia Richardson Khouri, Kathleen M Lutz, Leslie R Boyd.

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Perlmutter Cancer Center

Clinical Trials & Research Studies