A Phase 3 Open-Label Randomized Multi-Center Study of DZD9008 versus Platinum-Based Doublet Chemotherapy as First-Line Treatment for Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Exon 20 Insertion Mutation

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Nsclc Patients With Egfr Or Human Epidermal Growth Factor Receptor 2 (her2) Mutations.
  • Age: Between 18 Year(s) - 100 Year(s)
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Histologically or cytologically confirmed diagnosis of non-squamous NSCLC, locally advanced or metastatic
    2. Have written documentation of EGFR Exon20ins mutation in tumor tissue
    3. Participants should be newly diagnosed or have not received prior systemic treatment for locally advanced or metastatic NSCLC

You may not be eligible for this study if the following are true:

    1. Prior treatment with any systemic anti-cancer therapy for locally advanced or metastatic NSCLC
    2. Prior treatment with any EGFR Exon20ins inhibitors, including poziotinib, mobocertinib, CLN-081, furmonertinib, etc. or prior treatment with third generation of EGFR TKI, including but not limit to Osimertinib, Almonertinib, etc
    3. Major surgery within 4 weeks of the first study drug administration



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