OPTIMICE-PCR: DE-ESCALATION OF THERAPY IN EARLY-STAGE TNBC PATIENTS WHO ACHIEVE PCR AFTER NEOADJUVANT CHEMOTHERAPY WITH CHECKPOINT INHIBITOR THERAPY

Brief description of study

This study is for patients with early-stage triple-negative breast cancer who received a treatment called pembrolizumab (a medicine used to treat melanoma). Some patients will continue to get pembrolizumab, while others will simply be observed without more treatment. The main question is whether observation is as good as getting more pembrolizumab to prevent the cancer from coming back. The study looks at other things like side effects, quality of life, survival.

Clinical Study Identifier: s23-00607

Principal Investigator: Sylvia Adams.

Other Investigators: Yelena Novik, Maryann J Kwa, Douglas K Marks, Nina D'Abreo, Marleen I Meyers, Amanda Marie Talmadge, Danielle Seidman, Nancy Chan, Caitlin Elizabeth Ryan, Anastasiya Apanasyuk, Ruth Oratz, Natalie Jill Klar, Alexander A Hindenburg.

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Perlmutter Cancer Center

Clinical Trials & Research Studies