A Phase Ib/II Open-Label Multicenter Study Evaluating the Safety Activity And Pharmacokinetics of Divarasib in Combination with Other Anti-Cancer Therapies in Patients with Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer with a KRAS G12C Mutation

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A Phase Ib/II Open-Label Multicenter Study Evaluating the Safety Activity And Pharmacokinetics of Divarasib in Combination with Other Anti-Cancer Therapies in Patients with Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer with a KRAS G12C Mutation

Brief description of study

A Phase Ib/II, Open-Label, Multicenter Study Evaluating the Safety, Activity, And Pharmacokinetics of Divarasib in Combination with Other Anti-Cancer Therapies in Patients with Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer with a KRAS G12C Mutation

Clinical Study Identifier: s23-00228

ClinicalTrials.gov Identifier: NCT05789082

Principal Investigator: Vamsidhar Velcheti.

Other Investigators: Danny Perlaza, Samantha VanMaanen, Elka R Travis, Jessica Wang, Elaine Shum, Salman Rafi Punekar, James Newman, Joshua K Sabari, Marissa Rybstein, David Mendoza, Natalia Cherkassky, Sally Lau, Jeffrey G Schneider, Melissa L Martinez, Kirby Rodriguez.

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Perlmutter Cancer Center

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