A phase II/III Study of Paclitaxel/Carboplatin alone or Combined with either Trastuzumab and Hyaluronidase-oysk (HERCEPTIN HYLECTA) or Pertuzumab Trastuzumab and Hyaluronidase-zzfx (PHESGO) in HER2 Positive Stage I-IV Endometrial Serous Carcinoma or Carcinosarcoma
Brief description of study
This study is being done to answer the following question: Can we lower the chance of your endometrial cancer coming back and causing death by adding a drug or drugs that target HER2 proteins in addition to the usual combination of chemotherapy drugs that target HER2 proteins in addition to the usual combination of chemotherapy drugs?
Clinical Study Identifier: s23-00171
ClinicalTrials.gov Identifier: NCT05256225
Principal Investigator:
Whitfield B. Growdon.
Other Investigators:
Kent Chan,
Cindy Corbo,
Nitish Mehta,
Deanna Gerber,
Olivia Richardson Khouri,
Laura Palazzolo,
Marina Stasenko,
Jonathan B Kahn,
Fabia Brisard Pierrot,
Jagdeep Raince,
Leslie R Boyd,
Christina Grace Wilson,
Michelle Diane Swanson Lightfoot,
Emeline Mariam Aviki,
Carol M Lee,
Caitlin Elizabeth Ryan,
Victoria Helen Dowd,
Kelly A Levine,
Edward A Jimenez,
Erin Annette Reese,
Bhavana Pothuri,
Kathleen M Lutz.
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