Brightline-2: A Phase IIa/IIb open-label single-arm multi-centre trial of brigimadlin (BI 907828) for treatment of patients with locally advanced / metastatic MDM2 amplified TP53 wild-type biliary tract adenocarcinoma pancreatic ductal adenocarcinom

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Mdm2 Amplified, Tp53 Wild-type Biliary Tract Adenocarcinoma, Pancreatic Ductal Adenocarcinoma, Or Other Selected Solid Tumours
  • Age: Between 18 Year(s) - 100 Year(s)
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Biliary tract adenocarcinoma, pancreatic ductal adenocarcinoma, lung adenocarcinoma, or urothelial bladder cancer
    2. Be able to provide samples of tumor tissue preserved in a specific way (using formalin and paraffin)
    3. Adequate

You may not be eligible for this study if the following are true:

    1. Currently experiencing active bleeding, have a significant risk of hemorrhage (such as a history of severe gastrointestinal bleeding or a previous hemorrhagic stroke), or have a current bleeding disorder
    2. A major surgery within four we


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