A Randomized Open-label Phase 3 Study of Adjuvant Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician s Choice in Patients with Triple Negative Breast Cancer That Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery And Neoadjuvant Therapy
  • Age: Between 18 Year(s) - 100 Year(s)
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Patients must have a history of clinical stage T1, N1-2 or T2-4, N0-2 and histologically confirmed TNBC as determined by the investigator with residual disease in the breast or lymph node(s) after completion of neoadjuvant therapy and surgery
    2. Patients must have received neoadjuvant chemotherapy (taxane and/or anthracycline-based) with or without an aPD-(L)1 agent for a minimum of 6 cycles prior to surgery
    3. Patients must have received appropriate radiotherapy and have recovered prior to starting study treatment

You may not be eligible for this study if the following are true:

    1. Stage IV (metastatic) breast cancer
    2. Prior neoadjuvant HER2-directed therapy
    3. Patients with known germline BRCA mutations



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