Site for S2206 Phase III Trial of Neoadjuvant Durvalumab (NSC 778709) plus Chemotherapy versus Chemotherapy Alone for Adults with MammaPrint Ultrahigh (MP2) Hormone Receptor (HR) Positive / Human Epidermal Growth Factor Receptor (HER2) Negative Stage II-III Breast Cancer

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Mammaprint Ultrahigh (mp2) Hormone Receptor (hr) Positive / Human Epidermal Growth Factor Receptor (her2) Negative Stage Ii-iii Breast Cancer
  • Age: Between 18 Year(s) - 100 Year(s)
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Participants must have histologically confirmed ER positive and/or PR positive (hormone receptor positive) and HER2 negative breast cancer
    2. Participants must have clinical stage II or III breast cancer
    3. Participants must not have metastatic disease

You may not be eligible for this study if the following are true:

    1. Participants have locally recurrent breast cancer
    2. Participants have received any prior treatment for their current breast cancer, including chemotherapy, immunotherapy, biologic or hormonal therapy, and must be candidates for doxorubicin, paclitaxel, and durvalumab therapy
    3. Participants have a history of (non-infectious) pneumonitis that required steroids or evidence of active pneumonitis



If you are registered as a volunteer, please log in to contact the study team/express interest in this study.