A Phase 3 Randomized Double-blind Placebo- and Active-Comparator-Controlled Clinical Study of Adjuvant V940 (mRNA-4157) Plus Pembrolizumab Versus Adjuvant Placebo Plus Pembrolizumab in Participants with Resected Stage II IIIA IIIB (N2) Non-small Cell Lung Cancer

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Nsclc
  • Age: Between 18 Year(s) - 99 Year(s)
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Has surgically resected (R0) and histologically confirmed diagnosis of Stage II, IIIA, IIIB (with nodal involvement [N2]) squamous or nonsquamous NSCLC
    2. Confirmation that EGFR-directed therapy is not indicated as primary therapy (historical documentation of absence of tumor-activating EGFR mutations [eg, DEL19 or L858R] or as determined by either a local or the central laboratory)
    3. Has received at least one dose of adjuvant treatment with standard of care platinum doublet chemotherapy up to 4 cycles

You may not be eligible for this study if the following are true:

    1. Diagnosis of SCLC or, for mixed tumors, presence of small cell elements, or has a neuroendocrine tumor with large cell components or a sarcomatoid carcinoma
    2. HIV-infected participants with a history of Kaposi’s sarcoma and/or Multicentric Castleman’s Disease
    3. Received prior neoadjuvant therapy for their current NSCLC diagnosis



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