Site for PNOC027; A pilot trial of real time drug screening and genomic testing to determine an individualized treatment plan in children and young adults with relapsed medulloblastoma

Brief description of study

Site for The current study will use a new treatment approach based on the molecular characteristics of each participant's tumor. The study will test the feasibility of performing real-time drug screening on tissue taken during surgery, and of having a specialized tumor board assign a treatment plan based on the results of this screening and genomic sequencing. The aim of this trial is to allow every child and young adult with medulloblastoma to receive the most effective and least toxic therapies currently available, and will pave the way for improved understanding and treatment of these tumors in the future.


Clinical Study Identifier: s22-01577
ClinicalTrials.gov Identifier: NCT05057702
Principal Investigator: Jessica Clymer.
Other Investigators: Sharon L Gardner, Devorah Segal.


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