Perlmutter Cancer Center

This is a study looking at a new medicine called LY4101174. The study team wants to see if it has few effects and how well it works in treating the cancer in patients with advanced or metastatic cancers, including urothelial carcinoma. The study has two parts. In the first part, the study team will test different amounts of LY4101174 to find the dose with the fewest side effects for the next part of the study. The study team will also check if there is a need to adjust the dose based on side effects if there are any. The second part will involve more patients, and they will use the best dose with few side effects found in the first part. The study will focus on different types of cancers like breast, lung, ovarian, and other cancers. The study team wants to understand how this medicine works and if it helps patients with treating these cancers.