AN OPEN-LABEL MULTICENTER PHASE 1/2 STUDY TO EVALUATE THE SAFETY AND EFFICACY OF AB-3028 IN PATIENTS WITH CASTRATION RESISTANT PROSTATE CANCER (CRPC)
Are you eligible to participate in this study?
You may be eligible for this study if you meet the following criteria:
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Conditions: Prostate
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Age: Between 18 Year(s) - 99 Year(s)
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Gender: Male
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Other Inclusion Criteria:
In order to participate in this study, you must met the following conditions:- At least 18 years of age at time of signing informed consent form
- Prior prostate cancer treatment with at least 1 novel androgen receptor pathway inhibitor (ARPI) therapy (e.g. abiraterone acetate, apalutamide, enzalutamide, darolutamide)
- Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) 0 or 1
You may not be eligible for this study if the following are true:
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You will not be able to participate in this study if any of the following apply:
- Any prior systemic therapy for CRPC within 14 days prior to scheduled protocol required leukapheresis, except for maintenance hormonal therapy (e.g., gonadotropin releasing hormone agonist)
- Central nervous system (CNS) metastatic disease, leptomeningeal disease, or cord compression
- Subjects who received prior cellular therapy and experienced cellular therapy-related Grade 4 CRS or neurotoxicity, even if fully recovered
If you are registered as a volunteer, please log in to contact the study team/express interest in this study.