Pre-surgical Evaluation of Denosumab in Patients With Operable Invasive Breast Cancer

Brief description of study

The goal of this Phase 0 (biomarker) study is to evaluate tumor-specific biomarkers of RANK/RANKL expression in early breast cancer. It will also provide insight into changes in the tumor microenvironment induced by the RANKL inhibitor, denosumab, which may decrease the ability of tumor to spread.

Clinical Study Identifier: s14-01311 Identifier: NCTs14-01311