RADIation after no Axillary Nodal Sampling (RADIANS)
Brief description of study
This is a single arm, pilot, prospective study to evaluate the safety of partial breast irradiation in women who undergo breast conserving surgery without SLNB or ALND. Baseline demographic and clinical information will be collected. All patients will complete the BCTOS 13 questionnaire) and the Functional Assessment of Chronic Illness Therapy-Comprehensive Score for financial Toxicity (COST 1Q) Appendix A and B) at baseline and at 2 years. All patients are required to have an axillary ultrasound prior to radiation start if this was not obtained pre-operatively. Information will be collected on the radiation plan (dose and fractions), radiation techniques (prone vs. supine positioning, use of breath hold) and dosimetric data including the dose received by the ipsilateral level I and II axilla which will be contoured for all patients in the study. Information on breast cancer outcomes and endocrine therapy start and adherence will be collected annually for each patient for 5 years, either through direct follow up visits or from medical chart review supplemented with phone calls.
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