Utilizing Response- and Biology-Based Risk Factors to Guide Therapy in Patients with Non-High-Risk Neuroblastoma Response and Biology-Based Risk factor-guided therapy in treating younger patients with non-high Neuroblastoma

Brief description of study

This phase III trial studies how well response and biology-based risk factor-guided therapy works in treating younger patients with non-high risk neuroblastoma. Sometimes a tumor may not need treatment until it progresses. In this case, observation may be sufficient. Measuring biomarkers in tumor cells may help plan when effective treatment is necessary and what the best treatment is. Response and biology-based risk factor-guided therapy may be effective in treating patients with non-high risk neuroblastoma and may help to avoid some of the risks and side effects related to standard treatment.


Clinical Study Identifier: s15-00462
ClinicalTrials.gov Identifier: NCT02176967
Principal Investigator: Sharon L Gardner.
Other Investigators: William L Carroll, Gabriel Andrew Robbins, Joanna Pierro, Elizabeth Ann Roman, Theodore P Nicolaides, Linda Granowetter, Elizabeth A Raetz.


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