Perlmutter Cancer Center

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

• Conditions:
  Acute Myeloid Leukemia In Down Syndrome
• Age: Between 90 years - 4 years
• Gender: Male or Female

• Other Inclusion Criteria:
  

  1.  Children with Down syndrome > 90 days and < 4 years of age at diagnosis of AML or Myelodysplastic Syndrome (MDS)

   

  2.  Patients must have constitutional trisomy 21 (Down syndrome) or trisomy 21 mosaicism

   

  3.  Patients with previously untreated de novo AML who meet the criteria for AML with ≥ 20% bone marrow blasts

  
  

You may not be eligible for this study if the following are true:

• 1.  Children who previously received chemotherapy, radiation therapy or any anti-leukemic therapy (exception:  treated with cytarabine for Transient Myeloproliferative Disorder)

   

  2.  Patients with promyelocytic leukemia (FAB M3)