A Double Blind Placebo-Controlled Trial of Eflornithine and Sulindac to Prevent Recurrence of High Risk Adenomas and Second Primary Colorectal Cancers in Patients with Stage 0-III Colon or Rectal Cancer Phase III Preventing Adenomas of the Colon with Eflornithine and Sulindac (PACES)

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Colorectal Cancer
  • Age: Between 18 - 120 Years
  • Gender: Male or Female
  • Other Inclusion Criteria:

    1.  Patients must have a history of Stage 0, I, II, or III colon or rectal adenocarcinoma that has been treated per standard of care with resection alone or in combination with radiation and/or chemotherapy

     

    2.  Patients are able to swallow oral medications


You may not be eligible for this study if the following are true:

  • 1.  Patients that have received total proctocolectomy.

     

    2.  Patients with a known history of familial adenomatous polyposis, hereditary nonpolyposis colorectal cancer, or inflammatory bowel disease

     

    3.  Patients with known hypersensitivity to eflornithine or sulindac or the excipients byproducts.

     

    4.  High cardiovascular risk or uncontrolled hypertension




If you are registered as a volunteer, please login to the dashboard to send referrals.

Contact the research team to learn more about this study.

By clicking "Contact Research Team", your contact information will be sent securely to the research staff associated with the study. You will also receive a copy of this email in your inbox, as well as other notifications to determine your participation status in the study.