A Phase 1 Open-Label Multicenter Study to Assess the Safety Tolerability and Immunogenicity of mRNA-4157 Alone in Subjects with Resected Solid Tumors and in Combination with Pembrolizumab in Subjects with Unresectable Solid Tumors

Brief description of study

If you have been diagnosed with solid tumors, either removed previously by surgery or unresectable (locally advanced or metastatic), you may qualify for this phase 1 study testing the investigational drug mRNA-4157 alone or in combination with pembrolizumab. The main goal of this study is to study the safety of these drugs, and how well the body deals with effects of mRNA-4157 alone or in combination with pembrolizumab and to find the best dose for future studies of mRNA-4157 when given alone or when given with pembrolizumab.

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