A Phase 1 Open-Label Multicenter Study to Assess the Safety Tolerability and Immunogenicity of mRNA-4157 Alone or in Combination in Participants with Solid Tumors

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Resected Solid Tumors And Unresectable Solid Tumors
  • Age: Between 18 Year(s) - 100 Year(s)
  • Gender: Male or Female
  • Other Inclusion Criteria:
    Patients with any of the following solid malignancies: a. Non-small cell lung cancer lacking EGFR sensitizing mutant on or ALK translocation per local test results b. Small cell lung cancer c. Melanoma d. Bladder urothelial carcinoma e. Human papillo

You may not be eligible for this study if the following are true:

  • 1. Active central nervous system metastases and/or carcinomatous meningitis. 2. Active autoimmune disease that has required systemic treatment in past 2 years 3. Has a history of (noninfectious) pneumonitis that required steroids or current pneumon


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