TAILOR RT: A RANDOMIZED TRIAL OF REGIONAL RADIOTHERAPY IN BIOMARKER LOW RISK NODE POSITIVE BREAST CANCER

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Breast Cancer
  • Age: Between 40 - 100 Years
  • Gender: Female
  • Other Inclusion Criteria:
    1) Patients must have newly diagnosed histologically proven invasive carcinoma of the breast with no evidence of metastases. 2) Patients must have been treated by BCS or mastectomy. 3) Patient must consent to provision of, and investigator(s) must confirm access to and agree to submit to the CCTG Central Tumor Bank, a representative formalin fixed paraffin block of tumor tissue in order that the specific correlative marker assays described in the protocol may be conducted.

You may not be eligible for this study if the following are true:

  • 1) Patients with nodal disease limited to micrometastases (pN1Mi, > 0.2 mm and = 2 mm) or isolated tumor cells (pN0i+ < 0.2 mm). 2) Any prior history, not including the index cancer, of ipsilateral invasive breast cancer or ipsilateral DCIS treated with radiation therapy. (Patients with synchronous or previous ipsilateral LCIS are eligible.) 3) Synchronous or previous contralateral invasive breast cancer. (Patients with contralateral DCIS not treated with radiation are eligible.) 4) Patients with pT3 or pT4 disease.


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