The AIM-HN and SEQ-HN Study: A 2 Cohort Non-comparative Pivotal Study Evaluating the Efficacy of Tipifarnib in Patients with Head and Neck Squamous Cell Carcinoma (HNSCC) with HRAS Mutations (AIM-HN) and the Impact of HRAS Mutations on Response to First Line Systemic Therapies for HNSCC (SEQ-HN)

Brief description of study

The purpose of this research study is to see how effective the study drug is to treat your tumor. Other reasons for conducting the study are: • To determine for how long the study drug may reduce the size or slow down the growth of your tumor. • To determine the side effects of the study drug. • To study your tumor and determine why it responds or not to treatment with this study drug.

Clinical Study Identifier: s18-00146 Identifier: NCT03719690

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