Perlmutter Cancer Center

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

• Conditions:
  Malignant Pleural Mesothelioma
• Age: Between 18 years - 100 years
• Gender: Male or Female

• Other Inclusion Criteria:
  

  1) Has a confirmed histological diagnosis of MPM with histological type epithelioid or biphasic (predominantly [>50%] epithelioid). Histological diagnosis of MPM will be confirmed centrally using specimens or slides from tumor specimens obtained at the time of initial presentation or a subsequent procedure. 2) Has failed a minimum of 1 treatment regimen and a maximum of 2 treatment regimens, which may have been chemotherapeutic and/or immunotherapeutic treatment regimens for MPM which included at least 1 anti-folate and platinum combination regimen. Patients who have undergone primary surgical resection and/or radiation therapy to the pulmonary site are eligible to participate.
  

You may not be eligible for this study if the following are true:

• 1) Is "treatment-naïve" (i.e., has not received at least 1 anti-folate and platinum combination regimen). 2) Has previously received 3 or more lines of systemic chemotherapeutic or immunotherapeutic treatment. 3) Has previously received treatment with gemcitabine. 4) Has stage IV extrathoracic metastatic disease.