13 "Pancreas" clinical trials found.
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A Randomized Phase 2 Study of Losartan and Nivolumab in Combination with FOLFIRINOX and SBRT in Localized Pancreatic Cancer (Stand up to Cancer)
This multi-center, open-label, rando ized Phase II study will evaluate the effectiveness of the addition of the angiotension II type receptor blocker Losartan, or the ...
Phase
Interventional
Match Level: Exact
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PANOVA-3: Pivotal randomized open-label study of Tumor Treating Fields (TTFields 150kHz) concomitant with gemcitabine and nab-paclitaxel for front-line treatment of locally-advanced pancreatic adenocarcinoma
To test the efficacy and safety of gemcitabine and nab-paclitaxel, with or without TTFields, using the NovoTTF-100L(P) System as a front-line therapy for locally-advanced pancreatic ...
Phase
Interventional
Match Level: Exact
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A Phase I study of Anetumab Ravtansine in Combination with either Anti-PD-1 Antibody or Anti-CTLA4 and Anti-PD-1 Antibodies or Anti-PD-1 Antibody and Gemcitabine in Mesothelin-Positive Advanced Pancreatic Adenocarcinoma
The purpose of the study is to determine the side effects and best dose of anetumab ravtansine when given together with nivolumab, ipilimumab and gemcitabine ...
Phase
Interventional
Match Level: Exact
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DART: DUAL ANTI-CTLA-4 AND ANTI-PD-1 BLOCKADE IN RARE TUMORS
If you have been diagnosed with a rare cancer or a rare cancer of unknown primary origin, you may qualify for this study. The main ...
Phase
Interventional
Match Level: Exact
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A Phase 1/2 Study of Oral LOXO-292 in Patients With Advanced Solid Tumors Including RET Fusion-Positive Solid Tumors Medullary Thyroid Cancer and Other Tumors With RET Activation (LIBRETTO-001)
The purpose of this research study is to determine the safety of an investigational treatment called LOXO-292. LOXO-292 is an oral investigational drug that may ...
Phase
Interventional
Match Level: Exact
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A Phase 2 Study of Olaparib Monotherapy in Participants with Previously Treated Homologous Recombination Repair Mutation (HRRm) or Homologous Recombination Deficiency (HRD) Positive Advanced Cancer
The purpose of this study is to: • Test the safety of the study drug (olaparib), see how well the drug works, and see how ...
Phase
Interventional
Match Level: Exact
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A Phase 3 Randomized Double-Blind Study of Pamrevlumab or Placebo in combination with Gemcitabine Plus Nab-Paclitaxel as Neoadjuvant Treatment in Patients with Locally Advanced Unresectable Pancreatic Cancer
The purpose of this study is find out if the if the investigational drug, pamrevlumab, can be used to treat pancreatic cancer. FibroGen, Inc. (FibroGen), ...
Phase
Interventional
Match Level: Exact
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Precision Promise Platform Trial for Metastatic Pancreatic Cancer Precision PromiseSM
The purpose of this study is to hope that Precision PromiseSM will change the landscape of clinical development in pancreatic cancer and open the door ...
Phase N/A Interventional
Match Level: Exact
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A Phase 1-2 First-in-Human Study of CX-2029 in Adults with Metastatic or Locally Advanced Unresectable Solid Tumors or Lymphomas.
The study is being done to look at: • The possible side effects, safety and tolerability of CX-2029 • The highest dose of CX-2029 that ...
Phase
Interventional
Match Level: Exact
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A MULTI-CENTER OPEN LABEL PHASE 1/2 STUDY OF CYT-0851 AN ORAL RAD51 INHIBITOR IN PATIENTS WITH RELAPSED/REFRACTORY B-CELL MALIGNANCIES AND ADVANCED SOLID TUMORS
The purpose of the study to determine the safety of CYT-0851 in patients with relapsed/refractory B-Cell malignancies and advanced solid tumors. The study drug CYT-0851 ...
Phase
Interventional
Match Level: Exact
