18 "Pancreas" clinical trials found.
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A Randomized Phase 2 Study of Losartan and Nivolumab in Combination with FOLFIRINOX and SBRT in Localized Pancreatic Cancer (Stand up to Cancer)
This multi-center, open-label, rando ized Phase II study will evaluate the effectiveness of the addition of the angiotension II type receptor blocker Losartan, or the ...
Phase
Interventional
Match Level: Exact
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PANOVA-3: Pivotal randomized open-label study of Tumor Treating Fields (TTFields 150kHz) concomitant with gemcitabine and nab-paclitaxel for front-line treatment of locally-advanced pancreatic adenocarcinoma
To test the efficacy and safety of gemcitabine and nab-paclitaxel, with or without TTFields, using the NovoTTF-100L(P) System as a front-line therapy for locally-advanced pancreatic ...
Phase
Interventional
Match Level: Exact
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CREON (PANCRELIPASE) THERAPY FOR SUBJECTS WITH EXOCRINE PANCREATIC INSUFFICIENCY (EPI) DUE TO PANCREATIC CANCER: A DOUBLE-BLIND RANDOMIZED PARALLEL DESIGN WITH 2 DOSE COHORTS OF PANCRELIPASE IN RESECTED PANCREATIC CANCER SUBJECTS AND AN OPEN-LABEL SINGLE DOSE COHORT IN NON-RESECTED PANCREATIC CANCER SUBJECTS
The purpose of this study is to evaluate the effects of 2 different dose levels of pancrelipase on dietary fat absorption and exocrine pancreatic insufficiency ...
Phase
Interventional
Match Level: Exact
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A Phase I study of Anetumab Ravtansine in Combination with either Anti-PD-1 Antibody or Anti-CTLA4 and Anti-PD-1 Antibodies or Anti-PD-1 Antibody and Gemcitabine in Mesothelin-Positive Advanced Pancreatic Adenocarcinoma
The purpose of the study is to determine the side effects and best dose of anetumab ravtansine when given together with nivolumab, ipilimumab and gemcitabine ...
Phase
Interventional
Match Level: Exact
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A Phase 1 Open-Label Study of the Safety Tolerability and Efficacy of KPT-9274 A Dual Inhibitor of PAK4 and NAMPT in Patients with Advanced Solid Malignancies or Non-Hodgkin's Lymphoma (PANAMA)
if you are newly diagnosed with non-Hodgkin's lymphoma or advanced solid malignancies, you may qualify to participate in a clinical trial. The main goal ...
Phase
Interventional
Match Level: Exact
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DART: DUAL ANTI-CTLA-4 AND ANTI-PD-1 BLOCKADE IN RARE TUMORS
If you have been diagnosed with a rare cancer or a rare cancer of unknown primary origin, you may qualify for this study. The main ...
Phase
Interventional
Match Level: Exact
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A phase I open-label dose-escalation study to investigate the safety pharmacokinetics pharmacodynamics and clinical activity of GSK3368715 in participants with solid tumors and DLBCL
The purpose of this study is to test the safety, tolerability, and effectiveness of GSK3368715 (called the study drug from now on) for solid tumors ...
Phase
Interventional
Match Level: Exact
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A Phase 1/2 Study of Oral LOXO-292 in Patients With Advanced Solid Tumors Including RET Fusion-Positive Solid Tumors Medullary Thyroid Cancer and Other Tumors With RET Activation (LIBRETTO-001)
The purpose of this research study is to determine the safety of an investigational treatment called LOXO-292. LOXO-292 is an oral investigational drug that may ...
Phase
Interventional
Match Level: Exact
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A Phase 2 Study of Olaparib Monotherapy in Participants with Previously Treated Homologous Recombination Repair Mutation (HRRm) or Homologous Recombination Deficiency (HRD) Positive Advanced Cancer
The purpose of this study is to: • Test the safety of the study drug (olaparib), see how well the drug works, and see how ...
Phase
Interventional
Match Level: Exact
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A Phase 3 Randomized Double-Blind Study of Pamrevlumab or Placebo in combination with Gemcitabine Plus Nab-Paclitaxel as Neoadjuvant Treatment in Patients with Locally Advanced Unresectable Pancreatic Cancer
The purpose of this study is find out if the if the investigational drug, pamrevlumab, can be used to treat pancreatic cancer. FibroGen, Inc. (FibroGen), ...
Phase
Interventional
Match Level: Exact
