4 clinical trials found.
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An Open-Label Phase 1B/2 Study to Evaluate the Safety and Efficacy of Tabelecleucel in Combination with Pembrolizumab in Subjects with Platinum -pre-treated Recurrent /Metastatic Epstein-Barr Virus-Associated Nasopharyngeal Carcinoma
The purpose of this research study is to: • Assess the safety of tabelecleucel in combination with pembrolizumab. This will include looking at what side effects ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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MK-3475 (SCH 9000475) as neoadjuvant and adjuvant therapy in Stage III-IVA resectable
The purpose of this research study is to: • Test the safety of the study drug, pembrolizumab (MK-3475) • Test how your cancer responds to one of ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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Phase II: Adaptive De-escalation of Radiation Therapy Dose In Favorable Risk HPV-Positive Oropharyngeal Carcinoma (ART)
The main goal of this study is to determine if deescalating chemoradiation treatment based on early tumor shrinkage at mid-treatment can result in similar cancer ...
Phase
Interventional
TRIAL ROLE: Sub Investigator
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A PHASE 2 STUDY OF ALKS 4230 IN COMBINATION WITH ANTI-PD-1 (PEMBROLIZUMAB) IN PATIENTS WITH ADVANCED OR RECURRENT HEAD AND NECK SQUAMOUS CELL CANCER CURRENTLY ON TREATENT WITH ANTI-PD-(L)1 WITHOUT HAVING ACHIEVED A COMPLETE REMISSION
The purpose of this study is to see how well ALKS 4230 (IL-2 and IL-2 receptor (R; IL-2R)) works together with the drug Prembrolizumab to ...Phase
Interventional
TRIAL ROLE: Sub Investigator
