3 clinical trials found.
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A Phase 2 Open-label Multicenter Randomized Multidrug Platform Study of Neoadjuvant Durvalumab Alone or in Combination with Novel Agents in Subjects with Resectable Early-stage (I [> 2 cm] to IIIA) Non-small Cell Lung Cancer (NeoCOAST)
The main purpose of this study is to determine the effectiveness of durvalumab in combination with other experimental drugs to the effectiveness of durvalumab when ...
Phase
Interventional
TRIAL ROLE: Principal Investigator
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A Phase 1/2 Study of Oral LOXO-292 in Patients With Advanced Solid Tumors Including RET Fusion-Positive Solid Tumors Medullary Thyroid Cancer and Other Tumors With RET Activation (LIBRETTO-001)
The purpose of this research study is to determine the safety of an investigational treatment called LOXO-292. LOXO-292 is an oral investigational drug that may ...
Phase
Interventional
TRIAL ROLE: Principal Investigator
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A Phase 1 Study of ALKS 4230 in Subjects with Advanced Solid Tumors
This is a multicenter, open-label, Phase 1 study which will be conducted in 2 parts: a dose-escalation part and a dose expansion part. Patients ...
Phase
Interventional
TRIAL ROLE: Principal Investigator
