6 clinical trials found.
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First-in-human open-label dose-escalation trial with expansion cohorts to evaluate safety of GEN1046 in subjects with malignant solid tumors
The purpose of the study is to determine the safety of GEN1046 in patients with malignant solid tumors. GEN1046 is investigational drug in this study ...Phase
Interventional
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A Phase 1b/2 Open-Label Study to Evaluate the Safety and Efficacy of Lucitanib in Combination with Nivolumab in Patients with an Advanced Metastatic Solid Tumor
This is an open-label, Phase 1b/2 study to determine the recommended dose of lucitanib in combination with nivolumab in patients with an advanced solid ...Phase
Interventional
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A Two-arm Randomized Non-comparative Phase 2 Trial of AGEN2034 (anti PD-1) as a Monotherapy or Combination Therapy with AGEN1884 (anti-CTLA4) or with Placebo in Women with Recurrent Cervical Cancer (Second Line) - RaPiDS
In this research study, we are studying the Study Drugs AGEN2034 and AGEN1884 as immune therapies that target your immune cells to block proteins called ...Phase
Interventional
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Identification of Circulating Tumor Cells in Patients with HPV 16 or 18 Associated Cervical Cancer
The purpose of this study is to evaluate if a new test can find circulating tumor cells in the blood of certain patients with cervical ...Phase N/A
Observational
Accepts Healthy Volunteer
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A Phase 1/2 Open-Label Dose-Escalation Safety and Tolerability Study of NC318 in Subjects with Advanced or Metastatic Solid Tumors
The purpose of this research study is to learn about the effects of the study drug, NC318, when given as an investigational combination treatment for ...Phase
Interventional
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A Randomized Phase II Trial of Radiation Therapy and Cisplatin Alone or in Combination with Intravenous Triapine in Women with Newly Diagnosed Bulky Stage IB2 Stage II IIIB or IVA Cancer of the Uterine Cervix or Stage II-IVA Vaginal Cancer
If you have been diagnosed with locally advanced cervical or vaginal cancer, you may qualify for this Phase II study evaluating the investigational drug triapine ...Phase
Interventional
