45 clinical trials found.
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TH-189: A Phase 2 Study of Nivolumab plus Ramucirumab in Patients with Recurrent Advanced Metastatic Non-Small Cell Lung Carcinoma
This study will involve patients who have been diagnosed with non-small cell lung cancer, regardless of the specific type. These patients should have previously received ...
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A Phase 2 Study of Darolutamide in Combination with Leuprolide Acetate in Hormone-Therapy Na ve Recurrent and/or Metastatic Androgen Receptor (AR) Positive Salivary Gland Cancer
We want to study if combining two drugs, ADT and darolutamide, can help patients with a type of cancer called salivary gland carcinoma. We will ...
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A PHASE Ib/II OPEN-LABEL MULTICENTER STUDY EVALUATING THE SAFETY ACTIVITY AND PHARMACOKINETICS OF GDC-6036 IN COMBINATION WITH OTHER ANTI-CANCER THERAPIES IN PATIENTS WITH PREVIOUSLY UNTREATED ADVANCED OR METASTATIC NON?SMALL CELL LUNG CANCER WITH A K
This study is for people with advanced or metastatic non-small cell lung cancer (NSCLC) containing a specific KRAS G12C mutation. The study is testing a ...
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Phase 3 study evaluating AMG 757 Tarlatamab for patients with Small Cell Lung Cancer
This study is for patients with small cell lung cancer (SCLC). They want to see if a new treatment called tarlatamab (an immunotherapy that might ... -
Phase 1 First-in-Human Dose Escalation and Expansion Study to Assess Safety and Tolerability of Intravenous Administration of ICVB-1042 in Patients with Advanced Solid Tumors
This study is about a new medicine called ICVB-1042 (kills tumor cells) for people with advanced solid tumors. It has two parts: one where we ...
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A phase I open-label multi-center study of KFA115 as a single agent and in combination with tislelizumab in patients with select advanced cancers
This study is testing a new medicine called KFA115 (FDA approved) for patients with advanced or widespread cancers. It has two main parts: one where ...
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A Randomized Double-blind Multi-center Phase III Study of AK112 or Placebo Combined with Pemetrexed and Carboplatin in Patients with EGFRmutant Locally Advanced or Metastatic Non-squamous NSCLC Who Have Failed to EGFR-TKI Treatment
This study is to see if a new medicine called AK112 can help patients with advanced non-squamous non-small cell lung cancer (NSCLC) that didn't ...
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RevMed RMC-6236-001: A Phase 1/1b Multicenter Open-Label Study of RMC-6236 in Subjects with Advanced Solid Tumors Harboring Mutations in KRAS at Position G12.
This study is testing a new medicine, RMC-6236, for patients with certain advanced cancers that have specific changes in a gene called RAS. RMC-6236 aims ...
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A Phase I Multicenter Open-label First-in Human Dose Escalation and Expansion Study of AZD9592 as Monotherapy and in Combination with Anti-cancer Agents in Patients with Advanced Solid Tumors
This study is designed for patients diagnosed with advanced solid tumors. This is a study for the first time testing of a new medicine called ...
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Phase 1 First-In-Human Study to Explore the Safety Tolerability and Pharmacokinetics of AMG 305 in Subjects With Advanced Solid Tumors
This study is investigating a drug called AMG 305, which is designed to target specific cancer cells that have CDH3 and MSLN. This is a ...