Displaying 183 (all) recruiting clinical trials.
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A PHASE IB-II STUDY OF HIGH-DOSE POST-TRANSPLANT CYCLOPHOSPHAMIDE BORTEZOMIB AND ABATACEPT FOR THE PREVENTION OF GRAFT-VERSUS-HOST DISEASE (GVHD) FOLLOWING ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT)
The purpose of the study is to determine if the administration of the investigational prophylactic medications: PTCy, bortezomib and abatacept, for individuals with hematological malignancies ...
Phase
Interventional
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A Randomized Open-Label Phase 2 Study of a Patient-Specific Vaccine Targeting Neoantigens in Combination with Immune Checkpoint Blockade for Patients with Colon Cancer with Minimal Residual Disease Following Surgical Resection and Standard Adjuvant Chem
The purpose of the study is to determine the safety and effectiveness of the patient-specific-vaccine targeting neoantigens in combination with immune checkpoint blockade for patients ...
Phase
Interventional
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Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants with Melanoma (KEYNOTE-U02): Substudy 02C
The purpose of the study is to determine and to evaluate the safety as well as efficacy of investigational treatment arms with or without pembrolizumab ...Phase
Interventional
