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An Open-Label Prospective Multi-Center Randomized Clinical Trial to Evaluate The Efficacy and Safety Of TheraSphere Followed by Durvalumab (Imfinzi ) With Tremelimumab Versus TheraSphere Alone For Hepatocellular Carcinoma (HCC)
The purpose of this study is to objectively evaluate skin color changes during and after standard of care breast or chest wall radiotherapy using spectrophotometry ...
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A phase II trial of ImmunotheRapy with single fRactIon non-ablative raDIAtion in previously untreated patients with stage IV NSCLC. (IRRIDIATE-Lung trial).
You can participate in this study if you are diagnosed with advanced lung cancer. The primary goal of this trial is to evaluate the efficacy ...
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A SINGLE-ARM PHASE 2 STUDY OF DARATUMUMAB IN PREVIOUSLY TREATED STK11/LKB1 MUTATED NON-SMALL CELL LUNG CANCER
This is a study of a drug combination called daratumumab for patients with advanced lung cancer that has spread to other parts of the body ...
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Partial breast re-irradiation using ultra hypofractionation (PRESERVE)
This study is for patients who have had breast cancer come back in the same breast where they had surgery and radiation treatment before. This ...
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TH-189: A Phase 2 Study of Nivolumab plus Ramucirumab in Patients with Recurrent Advanced Metastatic Non-Small Cell Lung Carcinoma
This study will involve patients who have been diagnosed with non-small cell lung cancer, regardless of the specific type. These patients should have previously received ...
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A Phase 2 Study of Darolutamide in Combination with Leuprolide Acetate in Hormone-Therapy Na ve Recurrent and/or Metastatic Androgen Receptor (AR) Positive Salivary Gland Cancer
We want to study if combining two drugs, ADT and darolutamide, can help patients with a type of cancer called salivary gland carcinoma. We will ...
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A Phase II multicenter open-label single-arm dose escalation study of Asciminib monotherapy in 2nd and 1st Line Chronic Phase Chronic Myelogenous Leukemia (ASC2ESCALATE)
This study involves two groups of people with a type of blood cancer called chronic myeloid leukemia in its early stage. In one group, there ...
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A Phase 2 Randomized Study to Evaluate the Optimized Dose Safety and Efficacy of Livmoniplimab in Combination with Budigalimab for Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) Patients who Have Progressed After an Immune Checkpoint Inh
This research study aims to find out if two medicines, livmoniplimab (a special drug used to boost the body's ability to fight liver cancer ...
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Brightline-2: A Phase IIa/IIb open-label single-arm multi-centre trial of BI 907828 for treatment of patients with locally advanced / metastatic MDM2 amplified TP53 wild-type biliary tract adenocarcinoma pancreatic ductal adenocarcinoma or other se
The purpose of the trial is to study a drug called BI 907828 for the treatment of certain types of advanced or spreading tumors. These ...
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The Janus Rectal Cancer Trial: A Randomized Phase II Trial Testing the Efficacy of Triplet Versus Doublet Chemotherapy to Achieve Clinical Complete Response in Patients with Locally Advanced Rectal Cancer
This study will focus on improving chemotherapy response rates in both primary and metastatic rectal and colorectal cancer. In this study, patients will be divided ...