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An Open-label Multi-center Global Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX43 (Anti-PD-L1 ADC) in Subjects with Advanced Non-small Cell Lung Cancer (NSCLC)
This is a Phase 2 study testing different doses of a medicine called HLX43 for patients with advanced non-small cell lung cancer (NSCLC). HLX43 is ...
Phase
Interventional
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A Phase 2 Open-Label Study to Evaluate the Safety and Efficacy of Intravesical Instillation of TARA-002 in Adults with High-Grade Non-Muscle Invasive Bladder Cancer
Study TARA-002-101-Ph2 is an open-label Phase 2 study to investigate the safety and efficacy of TARA-002 administered intravesically in adults 18 years of age or ...Phase
Interventional
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TITLE: TRIPL: Thoracic Radiotherapy and Inhibition of PD-1 and LAG-3 for Locally Advanced Non-Small Cell Lung Cancer
This is a Phase II study testing a new treatment for people with locally advanced non-small cell lung cancer (LA-NSCLC). The goal of this study ...
Phase
Interventional
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A multicenter trial utilizing ctDNA Guided Triplet Boost for Patients following treatment on nivolumab and relatlimab in patients with metastatic melanoma
Multi-site trial utilizing ctDNA measurements to guide first-line therapy choice for patients with advanced or metastatic melanoma.Phase
Interventional
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Multi-Center Randomized Double-Blind Placebo-Controlled Trial Comparing Standard of Care Adjuvant Temozolomide With or Without 5-Aminolevulinic Acid (5-ALA) With Concomitant Low Intensity Diffuse Ultrasound (LIDU) Sonodynamic Therapy (SDT) System In Patients With Newly Diagnosed Glioblastoma After Completion of Chemoradiotherapy
This is a study testing a new treatment for patients with newly diagnosed glioblastoma (GBM), a type of brain cancer, after they have had surgery ...
Phase
Interventional
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PHASE 2 DOSE-RANGING AND INTERCEPTION STUDY OF LINVOSELTAMAB IN PATIENTS WITH HIGH-RISK MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE OR NON-HIGH-RISK SMOLDERING MULTIPLE MYELOMA
This is a Phase 2 study testing a medicine called Linvoseltamab (a fully human B-cell maturation antigen (BCMA)×CD3 bispecific antibody that targets BCMA on ...
Phase
Interventional
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An Open-label Single-Arm Phase 2 Study to Evaluate Enfortumab Vedotin plus Pembrolizumab for Bladder Preservation in Participants with Muscle-invasive Bladder Cancer
This is a global, open-label, phase 2 study in adult participants with histologically confirmed MIBC (stage cT2–T4aN0M0 or T1-T4aN1M0) who are eligible for RC ...Phase
Interventional
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A Phase 2 multicenter clinical study to evaluate the efficacy and safety of safusidenib erbumine in patients with isocitrate dehydrogenase 1 (IDH1)-mutant glioma
This is a Phase 2 study testing whether the new drug, safusidenib, is safe and effective in patients with glioma, a type of brain tumor ...
Phase
Interventional
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A Phase 2 Randomized Blinded Placebo-Controlled Trial Investigating the Efficacy and Safety of Visugromab versus Placebo in Combination with Pembrolizumab Pemetrexed and Carboplatin in First-Line Treatment of Participants with Metastatic Non-Squamous Non-Small Cell Lung Cancer (GDFATHER-NSCLC-01)
This is a Phase 2 study testing a new medicine called Visugromab (also called CTL-002) to see how well it works with standard cancer treatments ...
Phase
Interventional
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A Phase 2 Multicenter Open-Label Study Evaluating the Efficacy and Safety of TYRA-300 in Participants with FGFR3 Altered Low Grade Intermediate Risk Non-Muscle Invasive Bladder Cancer
This study will investigate the safety, tolerability of TYRA-300 and assess different doses of TYRA-300 in participants harboring FGFR3 mutations and/or fusions with intermediate ...Phase
Interventional
