Displaying 15 (all) recruiting clinical trials.
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Phase 3 Randomized Open-label Multicenter Study to Compare the Efficacy and Safety of Sacituzumab Tirumotecan in Combination with Pembrolizumab Versus Pembrolizumab Alone as First-line Maintenance Treatment in Participants with Mismatch Repair Proficient Endometrial Cancer (TroFuse-033/GOG-3119/ENGOT-en29)
This is a Phase 3 trial testing whether the study medicine sacituzumab tirumotecan (an antibody-drug conjugate, also known as sac-TMT, or MK-2870), when given in ...
Phase
Interventional
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A Phase 3 Randomized Open-label Study of Rinatabart Sesutecan (Rina-S) versus Treatment of Investigator s Choice (IC) in Patients with Platinum Resistant Ovarian Cancer (GOG 3107)
This study is being done to compare a new treatment, Rina-S, to standard chemotherapy in patients with a type of ovarian cancer that no longer ...
Phase
Interventional
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A Phase 2/3 Multicenter Randomized Study of Raludotatug Deruxtecan (R-DXd) a CDH6-directed Antibody-drug Conjugate in Subjects with Platinum-resistant High-grade Ovarian Primary Peritoneal or Fallopian Tube Cancer
This is a Phase 2/3 study aimed at learning more about the study medicine Raludotatug Deruxtecan (R-DXd) as a treatment for ovarian cancer patients ...
Phase
Interventional
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A Phase 3 Randomized Active-controlled Open-label Multicenter Study to Compare the Efficacy and Safety of MK-2870 Monotherapy Versus Treatment of Physician s Choice as Second-line Treatment for Participants with Recurrent or Metastatic Cervical Cancer (TroFuse-020/GOG-3101/ENGOT-cx20)
This is a Phase 3 study testing whether the study medicine MK-2870 is safer and more effective compared to the doctor's choice of other ...
Phase
Interventional
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A Phase 2 Single-Arm Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression (MAESTRA 1)
This is a phase 2 study to test whether the new study medicine, INCB123667 (CDK2 inhibitor), is safe and effective in patients with platinum-resistant ovarian ...
Phase
Interventional
