Displaying 223 (all) recruiting clinical trials.
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Accelerated Partial breast radiotherapy Study of a personalized Holder for prone breast Immobilization to Enhance Local Delivery (SHIELD)
This is a non-randomized study that looks at how well, how safely, and how easily a medical device called VENUS SHELL™ can be used during ...
Phase N/A
Interventional
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RADIation after no Axillary Nodal Sampling (RADIANS)
This is a single arm, pilot, prospective study to evaluate the safety of partial breast irradiation in women who undergo breast conserving surgery without SLNB ...Phase
Interventional
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A PHASE 1 OPEN-LABEL MULTICENTER STUDY OF JANX007 IN SUBJECTS WITH METASTATIC CASTRATION-RESISTANT PROSTATE CANCER
This study is a first-in-human (FIH), Phase 1, open-label, multicenter study to assess the safety, tolerability, PK, PD, and preliminary efficacy of JANX007 administered as ...Phase
Interventional
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Safely Optimizing Body Weight with TCMCB07 in Patients with Newly Diagnosed Metastatic Colorectal Cancer Undergoing Chemotherapy
This is a study testing different doses of a drug called B07 (an experimental drug) to see how it affects body weight, BMI (body mass ...
Phase
Interventional
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A Phase 3 Multi-regional Open-label Randomized Study of Tirabrutinib vs Rituximab and Temozolomide in Participants With Relapsed/Refractory Primary Central Nervous System Lymphoma
This is a Phase 3 study testing how well and how safely tirabrutinib (a second-generation BTK inhibitor) alone works compared with R-TMZ (rituximab plus temozolomide ...
Phase
Interventional
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A Phase 2 study to investigate efficacy safety tolerability and pharmacokinetics of JZP3507 (ONC206) in adults with recurrent Grade 2 or 3 Meningioma
This is a Phase 2 study testing a new drug called JZP3507 (an investigational anti-cancer drug) in patients with Grade 2 or Grade 3 meningioma ...
Phase
Interventional
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A Phase 1 First-in-Human Study to Investigate the Safety Pharmacokinetics and Preliminary Efficacy of ML261 an Autologous Anti-DLL3 CAR + CARD11-PIK3R3 Fusion T cell therapy in Participants with Relapsed/Refractory Small Cell Lung Cancer or Select Neuroendocrine Carcinomas
This is a Phase 1, first-in-human study that is testing a new treatment called ML261 for people with certain types of cancer, specifically small cell ...
Phase
Interventional
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A Phase 1b Study Evaluating the Safety Tolerability pharmacokinetics and Efficacy of Tarlatamab in Combination with ZL-1310 with or without Anti-PD-L1 in Participants with Small Cell Lung Cancer
This is a Phase 1b study testing tarlatamab together with ZL-1310 (an investigational drug), with or without an immune therapy called anti-PD-L1 (durvalumab), in people ...
Phase
Interventional
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Phase 1/1b Multicenter Open-Label Study of RMC-5127 in Patients with Advanced KRAS G12V-Mutant Solid Tumors
This is a Phase 1/1b study testing RMC-5127 (investigational cancer drug) in adults with advanced solid tumors that have a KRAS G12V mutation, a ...
Phase
Interventional
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Randomized Phase 2 Trial of Ruxolitinib in Combination with Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma
This is a Phase 2 study testing a new treatment approach for newly diagnosed glioblastoma. It compares ruxolitinib plus radiation and temozolomide to the standard ...
Phase
Interventional
